Libraries Catalog

Descriptions

Diverse covalent library with most demanded warhead types

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Designed for discovery of mild electrophilic inhibitors of the largest enzyme class

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Designed for the discovery of new SARS-CoV-2 and pan-Coronavirus antivirals

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Diverse covalent warheads with balanced reactivity

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Library of Cys-specific covalent electrophilic binders

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Special selection of Serine focused irreversible binders

Description

The ultimate selection of Lys-specific binders

Descriptions

Characterized by a new HTS thiol-reactivity assay

Descriptions

Diverse screening Acrylamides pre-plated at 10 mM concentration

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Representative selection of fragment Acrylamides pre-plated at 100 mM stock concentration

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Library of diverse HTS-size chloroacetamides pre-plated at 10 mM concentration

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Diverse strict Ro3 compliant chloroacetamides plated at 100 mM stock concentartion

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Representative selection of N-, O-linked and Aryl sulfonyl fluorides within fragment space

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Designed and specially synthesized for the discovery of new Immunomodulatory Imide Drugs

Descriptions

A special selection of new Avadomide analogs

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Designed to cover all structural diversity of CRBN binders, a key component of the E3 ubiquitin ligase complex

Descriptions

A small selection of diverse covalent binders capable of interacting with CRBN

Descriptions

A versatile tool for discovering new VHL-based degraders

Descriptions

Designed to target DCAF family of E3 ligases

Descriptions

Library of compounds intended for use in agro/crop science

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Designed for discovery of novel allosteric ligands

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Carefully selected molecules via docking and visual evaluation

Description

Designed for the discovery of novel antibacterials

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Designed for discovery of new Nucleoside-like antivirals

Description

Specially selected molecules to target bromodomains

Descriptions

Designed for discovery of new Voltage-gated calcium channel blockers

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Library of novel small molecules with high CNS MPO scores

Descriptions

Designed for the discovery of new SARS-CoV-2 and pan-Coronavirus antivirals

Description

Designed for identification of new actives against proteins essential for DNA stability

Description

Library of compounds focusing to hit on a number of epigenetic targets

Description

Designed to effectively target the receptor and block estrogen release

Descriptions

Specially synthesized set of compounds able to mimic glycosides and their interaction with proteins

Descriptions

Designed for discovery of new GPCR ligands

Descriptions

Designed for discovery of novel kinase ATP pocket binders

Descriptions

IDO focused library designed by a combination of structure- and ligand-based methods

Descriptions

Designed for discovery of new Ion Channels ligands

Description

Designed for efficient hit finding against a number of immune disorders, including RA

Descriptions

Designed for discovery of novel protein kinase inhibitors

Description

Designed for discovery of new regulators of methabolic disorders

Descriptions

A sub-library of Enamine’s GPCR Library designed for discovery of novel lipid GPCR ligands

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A set of compounds focused on targeting molecular chaperones

Descriptions

Small library of specially synthesized compounds

Descriptions

Sublibrary of PPI-40

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Selected molecules able to mimic common protein motifs

Descriptions

Designed for discovery of novel PPI inhibitors

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Designed to promote the discovery of new-generation medicine

Descriptions

Designed for discovery of mild electrophilic inhibitors of the largest enzyme class

Descriptions

Designed for discovery of new Nav1.7 channel blockers

Description

Represents the diversity of structures and molecular targets of all FDA-approved chemical entities (Nat Chem Biol 13 (2017), 771–778)

Descriptions

Actives with extensive target classes’ coverage and the broadest possible therapeutic areas applications – from CNS agents and anti-infectives to anticancer drugs, steroids and molecular glues.

Description

Most relevant selection of drugs in one formulation/no duplicates. Contains WHO List of Essential Medicines including Lapatinib and latest approved drugs such as Tivozanib, etc.

Description

Compounds with referred biological activity for repurposing or investigation of new pathways and mechanisms

Description

Library of cell penetrated compounds and their closest analogs. Covers diverse therapeutic areas from antitumor, neurology and antibacterial to aging diseases.

Description

Frequent hitters with most diverse scaffold selection – from small hydroquinone and other covalent modifiers to polyfluorinated highly lipophilic molecules and dyes.

Description

Elaborated tool for initial screen

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Fragments of high MedChem tractability

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Designed for easy and rapid follow-up synthesis

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Guiding optimisation of fragment-derived lead compounds

Description

Diverse covalent warheads with balanced reactivity

Description

Specially designed for 19F NMR ligand-based screening

Description

Designed for easy and efficient exploration of novel protein targets

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Source of biologically validated starting points

Description

Unique 3D diversity among shaped molecules

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Fragments able to mimic protein structural motifs and hot-spot residues

Description

Fragments for easy-to-analyse protein-ligand interaction

Description

Designed for specific protein targets and sensible onset

Description

The most medchem reliable source of carboxylic acids replacement

Description

Characterized by a new HTS thiol-reactivity assay

Description

Covalent Heterocyclic Fragment Library for identification of Cryptic and Allosteric Pocket

Description

CNS-friendly molecules capable of BBB penetration

Description

Enantiomeric pairs of covalent electrophilic fragments