with Enamine Discovery
We live in a thrilling new era of drug discovery, benefiting from a plethora of well-established and continuously developing scientific modalities, empowered now by artificial intelligence. They enable lightning-fast access to the lead compounds in various therapeutic areas. However, this powerful modern toolkit frequently works on outdated chemical libraries historically available at pharma companies, CROs and screening centers.
Our integrated discovery approach harnesses the world’s leading CRO’s best practices in the integrated drug discovery and capitalizes on:
- Smart selection from Enamine’s latest screening libraries
- Cost control and fast progress in Enamine REAL
- Unique chemistry knowledge accumulated at Enamine
Innovation in drug discovery should be accessible - without losing quality. We offer a fast, cost-efficient start powered by smart libraries, a colossal stock of building blocks, and our REAL technology. This lets us quickly find and prioritize the right compounds, speed up the DMTA cycle, and boost early-phase results.
Whether you come with a validated target, a phenotypic readout, or a disease model, we tailor our approach to fit your specific needs. From early screening to biology and pharmacology, our MedChem experts and project leaders guide each stage with precision, quality, and efficiency.
Our MedChem board brings focus and expertise to every stage. They help set clear priorities, make informed decisions, and keep the project on track—from target evaluation to candidate selection.
Target Evaluation & Validation
We assess biological relevance, druggability, and therapeutic potential to prioritize the right targets.
Target Product Profile (TPP)
We help define key product criteria: mechanism of action, clinical use, and differentiation strategy.
Hit Generation & Screening Strategy
We design efficient screening campaign with the right libraries, technologies, and assays to deliver meaningful hits.
Hit to Lead
We support SAR development, ADME profiling, and synthetic planning to refine hit series into lead candidates.
Lead Optimization
We guide compound design to improve potency, selectivity, and developability—aligned with your TPP.
Candidate Selection
We help integrate efficacy, safety, and PK data to select the best candidates with confidence.
Unique Enamine drug discovery platform
We don't just bring together what already exists at Enamine. We connect the dots and orchestrate all available services and products into a seamless solution.
