search
Login Form

Enamine Fragment Collection currently contains 259 380 fragments being the largest and most reliable source of quality fragments. A number of focused fragment libraries were designed to perfectly meet needs of our clients. We collaborate with the leading experts in FBDD field on design and supply of top fragment libraries.

Product name
Size
Description
Download file

Size

320
compounds

Description

Elaborated tool for initial screen

Download file

&nsbp;

Size

1 920
compounds

Description

Fragments of high MedChem tractability

Download file

&nsbp;

Size

860
compounds

Description

Designed for easy and rapid follow-up synthesis

Download file

&nsbp;

MiniFrag Library

MiniFrags-80

Size

80
compounds

Description

Guiding optimisation of fragment-derived lead compounds

Download file

&nsbp;

Size

8 480
compounds

Description

Diverse covalent warheads with balanced reactivity

Download file

&nsbp;

Size

1 000
compounds

Description

Specially designed for 19F NMR ligand-based screening

Download file

&nsbp;

Size

800
compounds

Description

Designed for easy and efficient exploration of novel protein targets

Download file

&nsbp;

Size

4 160
compounds

Description

Source of biologically validated starting points

Download file

&nsbp;

Size

1 200
compounds

Description

Unique 3D diversity among shaped molecules

Download file

&nsbp;

Size

3 600
compounds

Description

Fragments able to mimic protein structural motifs and hot-spot residues

Download file

&nsbp;

Size

1 500
compounds

Description

Fragments for easy-to-analyse protein-ligand interaction

Download file

&nsbp;

Size

4 000
compounds

Description

Designed for specific protein targets and sensible onset

Download file

&nsbp;

Halogen-enriched Fragment Library

Size

3 000
compounds

Description

Library of high diversity of halogen bonding motifs

Download file

Size

960
compounds

Description

Characterized by a new HTS thiol-reactivity assay

Download file

&nsbp;

Size

141
compounds

Description

Covalent Heterocyclic Fragment Library for identification of Cryptic and Allosteric Pocket

Download file

&nsbp;

Size

1 280
compounds

Description

CNS-friendly molecules capable of BBB penetration

Download file

&nsbp;

Size

960
compounds

Description

Enantiomeric pairs of covalent electrophilic fragments

Download file

&nsbp;

Support

  • Hit Confirmation: QC check, HPLC repurification, resynthesis
  • Hit follow-up: analogs search from stock or REAL Database
  • Fast hit exploration libraries synthesis

We offer comprehensive support in developing your hit compounds. Naturally such programs are realised most efficiently when biological actives originate from our screening collection. However, even if the hit compounds are from the collections of other vendors lead identification and optimization projects can proceed most productively in our hands. Sometimes for this we only need to synthesize first examples of the given chemical series and validate synthesis route.

 

Contact Us