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Compounds with annotated activity data

more than 15,000 compounds

Our Bioactive Collection brings together over 15,000 compounds with documented biological activity. This includes around 1,200 FDA-approved drugs, as well as tool compounds, metabolites, prodrugs, and drug candidates currently in clinical trials.

Through our collaboration with Pfizer, Enamine also offers a curated selection of Pfizer Reference Compounds EnamineStore — including exploratory molecules, research tools, investigational drugs, and isotope-labeled standards. All compounds are fully characterized and quality-controlled, providing trusted tools for drug discovery research.

  • Data you can rely on
    Every compound is fully annotated with literature references and biological activity data.
  • Custom sourcing
    Need something beyond the catalog? We can deliver almost any compound through in-house synthesis or our global supplier network.
  • Expand with analogs
    Discover analogs through searches across 76.9B compounds across our Screening Collections, REAL Database and REAL Space or by enumeration of new hit follow-up libraries.

A comprehensive searchable database including literature references and activity/selectivity values towards different targets is available through a custom request form.

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