One Partner for Early Drug Discovery
Our catalog of over 4.7M+ Screening Compounds, 350K+ Building Blocks, and fully integrated CRO services - spanning chemistry, biology, and computer science ensure smothness, quality, and speed at every stage of your research. Founded in Kyiv in 1991, we have spent over three decades earning the trust of pharmaceutical companies, biotech organizations, and academic institutions across the globe.
in drug discovery
Scientists
Building blocks in stock
screening compounds
REAL Compounds
Countries served globally
Integrated Capabilities
From compound synthesis to biological testing and in silico modeling, we provide all the expertise you need for preclinical Drug Discovery in one place.
Chemistry
Enamine delivers custom synthesis of single compounds and focused libraries from milligram to kilogram scale, supported by FTE chemistry teams and access to over 350K Building Blocks. Our capabilities span multistep organic synthesis, asymmetric synthesis, metal-mediated reactions, and complex targets.
Biology
Our Biology Team provides comprehensive preclinical testing including high-throughput screening (HTS), in vitro ADME, in vivo PK/Tox, physicochemical profiling, screening by mass spectrometry, and recombinant protein production. Our capabilities cover everything needed to progress candidates through the discovery pipeline.
Computer-Aided Drug Design
Our computational chemists combine molecular modeling, AI-powered screening, and direct access to the Enamine REAL Space and screening libraries - covering everything from target identification and structure prediction to lead optimization, with a seamless transition from virtual hits to synthesis and biological validation.
35 Years of Growth and Discovery
From a small screening compound provider in Kyiv to a globally recognized chemistry partner for leading pharmaceutical companies worldwide.
1991
FoundationFoundation Year
Enamine was founded in Kyiv, Ukraine to support High-throughput screening with novel small-molecule libraries.
1991
InnovationThe creation of Enamine REAL® (REadily AccesibLe) approach
Creating a new approach for readily accessible molecules for Drug Discovery, introducing a concept for parallel synthesis in 2–3 steps.
1996
Company GrowthThe first 50 Chemists on board
Reaching a Team of 50 chemists marked an important milestone in Enamine’s early growth and research capabilities.
1999
Catalog Expansion1 million in-stock Screening Compounds
Achieved a major milestone by building the industry's largest collection of commercial available Screening Compounds.
2006
InnovationThe Launch of Enamie MADE (MAke-on-DEmand) Building Blocks
Introducing make-on-demand Building Blocks supported by validated synthesis routes and from the in-stock starting materials.
2011
Discovery ServicesThe launch of Enamine Biology Services
Opening biology labs for screening and ADMET testing services.
2013
Catalog ExpansionEnamine REAL® Space size: 25 million molecules
The REAL® Space continued to grow, offering researchers access to a diverse chemical universe.
2014
Discovery ServicesThe launch of FTE Department
Providing dedicated chemistry teams to support medicinal chemistry and Drug Discovery projects.
2015
Catalog Expansion100K in-stock Building Blocks
Reaching 100,000 off-the-shelf available compounds.
2015
Catalog Expansion100 million MADE Building Blocks
Giving the research commercial-ready-to-order molecules reduces the need for custom chemistry.
2019
Company Growth500 Chemists on board
A major milestone in building one of the industry's largest scientific teams.
2019
Catalog Expansion1 billion MADE Building Blocks
Reaching a scale that transformed access to the novel compounds.
2020
Catalog Expansion200K in-stock Building Blocks
Doubling the in-stock collection to 200,000 compounds, making more mol available for immediate use.
2021
INNOVATIONEnamine REAL® Space size: 20 billion molecules
Expanding chemical diversity to a scale that dramatically changes early Drug Discovery.
2023
CATALOG EXPANSIONThe Launch of Enamie Fast MADE Building Blocks - 100 million
Combining vast compound selection with accelerated delivery terms.
2025
Discovery ServicesThe launch of Integrated Drug Discovery (IDD) Platform
Providing end-to-end Drug Discovery support from target selection to a validated hit.
2026
ANNIVERSARY35th anniversary Enamine Drug Discovery Сonference
Our Values
Respect
Our strength comes from our people. We cultivate a culture of mutual respect - within our teams and with every client and partner we work with - where different backgrounds and perspectives are valued.
Teamwork
1500+ scientists. Dozens of disciplines. One shared goal. At Enamine, collaboration isn't a buzzword - it's how we've built one of the world's largest chemistry teams and kept it at the forefront for over 35 years.
Social Responsibility
Our growth is global. Our responsibility is too. Across four continents, we uphold one commitment: to operate ethically, support education, and make a meaningful difference in every community we serve.
Proactivity
Proactivity is one of the qualities we admire most in our people. We encourage every employee to take initiative, seek improvement, and step up - knowing that the best ideas often come from those closest to the work.
Professionalism
Enamine guarantees its clients and partners the highest level of competence. We work as one team, continuously learning and developing skills to perform at our best. Our commitment ensures lasting value for all we serve.
Why Enamine?
Scale, expertise, reliability - four reasons researchers choose Enamine.
01
Global Infrastructure, Local Expertise
With headquarters in Kyiv and operations in Germany, Latvia, Poland, and the USA, Enamine combines global reach with deep regional expertise. Our presence across four continents allows us to respond quickly and effectively to the needs of clients at every stage of their research. Stock facilities across Europe and North America ensure fast, reliable delivery wherever your program takes place.
02
The Largest Commercially Available Collection
Access to the right compound at the right time can define the success of a project. Enamine maintains the most extensive in-stock catalog in the industry - over 4.8M+ Screening Compounds and 370K+ Building Blocks, available for immediate dispatch. Our collection is continuously expanded with novel, drug-like structures, ensuring that whatever your project requires.
03
One Partner for the Entire Discovery Workflow
From compound procurement and custom synthesis to library design, biological screening, ADMET testing, CADD, and in vivo studies - Enamine covers the full drug discovery process under one roof. Our co-located chemistry and biology teams work in close collaboration, eliminating delays, reducing friction, and maintaining continuity of data and knowledge throughout your entire program.
04
Three Decades of Science, Expanding Every Day
Founded in 1991, Enamine has grown from a small chemistry team into a global organization of 3,500+ employees, serving pharmaceutical companies, biotech firms, and academic institutions across 50+ countries. We expand our catalog, our services, and our scientific capabilities every year. That continuous growth is not just history - it is the foundation every project is built on.
Explore Our Platforms
Enamine is more than one company. Our family of specialized organizations extends our scientific reach - from frontier biology services to dedicated academic research.
Biology Services & Screening
Enamine Biology delivers expert in vitro pharmacology, bioanalytical and ADME/Tox screening, biochemical assay development, and molecular screening programmes. Over 40% of our biology team hold a PhD, serving clients across 20+ countries.
In vitro pharmacology ADME HTS Screening
Academic & Fundamental Research
The Enamine Scientific Research Institute drives fundamental research in organic and medicinal chemistry, fostering collaborations with Ukrainian universities, the National Academy of Sciences, and international academic partners. Home to ERC-funded projects and open-science initiatives.
Organic chemistry ERC Funded Academic partnerships
Your Next Chapter Starts Here
We are always looking for exceptional chemists, researchers, and scientists who want their work to truly matter. At Enamine, you won't just run reactions — you'll contribute to discoveries that shape the future of medicine, working alongside some of the brightest minds in the field. We offer a dynamic, collaborative environment where scientific ambition is celebrated and career growth is real. If you're ready to do the most meaningful work of your career, we'd love to hear from you.
Pushing the Boundaries of Drug Discovery
Enamine's scientists publish 120+ articles annually, actively shaping the field.
Enamine Ltd.: The Science and Business of Organic Chemistry and Beyond
A review of Enamine's 30-year journey — covering the REAL approach, BB innovation, CRO growth, and scientific contributions to drug discovery worldwide. Published in the EU Journal of Organic Chemistry.
Difluorobicyclo[1.1.1]pentane as an Isosteric Replacement for Benzene
Enamine scientists introduced df-BCP as a benzene isostere — matching molecular volume while boosting sp3 character and solubility. Now widely adopted in modern medicinal chemistry programs globally.
COVID Moonshot: Open-Science Discovery of SARS-CoV-2 Main Protease Inhibitors
Enamine served as a principal chemistry partner in the COVID Moonshot collaboration — synthesising compounds for a global, open-access effort to develop novel SARS-CoV-2 antiviral drug candidates.