Designed for specific protein targets and sensible onset
4 000 compounds
In response to high demand for new and small carboxylic acid we have created set of carefully selected specific molecules that strictly respond to FBDD requirements. Our carboxylic acid fragments are mainly consist from the compounds derived in the last three years from previously established at Enamine in-house program for design and producing diverse carboxylic acids to enlarge core Building Blocks Collection and diversification of decorating reagents.
Mainly this type of fragments has great potential for hit finding on new and difficult targets, e.g. protein-protein interaction, due to binding affinity to so called “hot-spot” residues. In addition there is probability of high solubility and good membrane permeability of discovered initial hit that often could be a limiting factor for phenotypic screening or in vivo activity of following investigation.
Typical Formats
Catalog No.
CAF-4-10-Y-100
Compounds
4 000
13 plates
Amount
10 µL of 100 mM solutions in DMSO
Plates and formats
384-well plates, Echo qualified Labcyte LP0200; 1, 2 and 23, 24 columns empty; 320 compounds per plate
Price
Catalog No.
CAF-4-50-X-100
Compounds
4 000
50 plates
Amount
50 µL of 100 mM solutions in DMSO
Plates and formats
96-well plates, Greiner Cat. No 650201, 1 & 12 columns empty, 80 compounds per plate
Price
Catalog No.
CAF-4-100-X-10
Compounds
4 000
50 plates
Amount
100 µL of 10 mM solutions in DMSO
Plates and formats
96-well plates, Greiner Cat. No 650201, round (U) bottom, 1 & 12 columns empty, 80 compounds per plate
Price
Download SD file
Key features
- High novelty and core diversity
- Fast follow-up with stock available analogues & synthesis
- Cherry-picking is available, customer preferred delivery format
