CLOUD
The comprehensive Drug Collection
281 compounds
To date no commercially available compound collection covered all drug classes, resulting in complications in combinatorial screening attempts. We collaborated with a group of researchers at CeMM and collected a condensed screening set of 281 small molecules representing the entire target and chemical space of all FDA-approved drugs. The CeMM Library of Unique Drugs (CLOUD) covers prodrugs and active forms at pharmacologically relevant concentrations and is ideally suited for combinatorial studies. Recent publication [1] provides evidences of successful drug repurposing by pairwise compound screening from CLOUD collection in cancer cell viability assay. The findings highlight that refined chemical library CLOUD is a powerful tool for drug repurposing and evaluation of new substances suitable for all high-content and high-throughput assays.
CLOUD is now available for immediate supply in the following most popular pre-plated formats
Typical Formats
Catalog No.
CLOUD-Y-0
Compounds
281
Amount
≤ 1 µL of 10 mM of DMSO solutions
Plates and formats
384-well eco-qualified assay ready microplates, Greiner/Labcyte
Price
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Catalog No.
CLOUD-Y/X-10
Compounds
281
Amount
10 µL of 10 mM of DMSO solutions
Plates and formats
384-well or 96-well plates, eco-compatible
Price
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Catalog No.
CLOUD-Y/X-50
Compounds
281
Amount
50 µL of 10 mM of DMSO solutions
Plates and formats
384-well or 96-well plates, eco-compatible
Price
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Catalog No.
CLOUD-293
Compounds
281
Amount
Custom
Plates and formats
Any custom format
Price
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Key features
- Covers all therapeutically significant space of approved drugs.
- Contains prodrugs and active metabolites at pharmacologically relevant concentrations.
- Ideally applicable for combinatorial assays to study new drug combinations.
- Most structurally diverse drug library among commercially available collections.
- Immediately accessible in convenient pre-plated formats with carefully prepared detailed documentation. The library can be also made in any customized ready-to-screen formats.
Examples of drugs in the library

CLOUD147Iloprost

CLOUD019Clopidogrel

CLOUD014Norcisapride

CLOUD003Chloroquine
Selection and library evolution scheme


[1] Nature Chemical Biology 13, 771–778 (2017).