Discovery Diversity Set

A top-quality diverse library of recently synthesized compounds

50 240 compounds

The success of high throughput screening in finding decent starting points for drug discovery heavily depends on the quality of the compound library. Compound screening libraries nowadays must bear an essential degree of novelty, possess contemporary lead-like properties and be built on “live chemistry” that can supply related chemical entities.

 

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Enamine is constantly updating its Screening catalog with at least 225 000 newly synthesized compounds each year. These molecules are built on novel chemistry with use of the latest achievements in parallel chemistry and following industry trends in molecular properties and structural features. Every new library to be synthesized went through serial filters and is focused to bring novelty in a certain drug discovery area.

 

Discovery Diversity Sets (DDS) are aimed to bring latest chemistry to our customers within a smart clustering approach. Discovery Diversity Sets are based only on the lead-like compounds including representatives of all three main screening collections – HTS, Advanced, and Premium.

Typical Formats

Catalog No.
Compounds
Amount
Format*
Price

Catalog No.

DDS-50-0-Z-2

Compounds

50 240
40 plates

Amount

≤ 300 nL of 10 mM or lower DMSO solutions

Plates and formats

1536 well, Echo Qualified 001-6969 (LP-0400), first four and last four columns empty, 1280 compounds per plate

Price

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Catalog No.

DDS-50-10-Y-10

Compounds

50 240
157 plates

Amount

10 µL of 10 mM DMSO solutions

Plates and formats

384 well, Echo Qualified LDV microplates 001-12782 (LP-0200), first and last two columns empty, 320 compounds per plate

Price

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Catalog No.

DDS-50-50-Y-10

Compounds

50 240
628 plates

Amount

50 µL of 10 mM DMSO solutions

Plates and formats

384 well, Greiner Bio-One microplates 781280, first and last two columns empty, 320 compounds per plate

Price

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Catalog No.

DDS-50

Compounds

50 240

Amount

Custom

Plates and formats

Any custom format

Price

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*We will be happy to provide our library in any other most convenient for your project format. Please select among the following our standard microplates: Greiner Bio-One 781270, 784201, 781280, 651201 or Echo Qualified 001-12782 (LP-0200), 001-14555 (PP-0200), 001-6969 (LP-0400) or send your preferred labware. Compounds pooling can be provided upon request.

The hits derived from Discovery Diversity Sets are expected to be fast and easy to follow up with readily accessible parallel chemistry.

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Discovery Diversity Set

Library code: DDS-50

Version: 2 February 2024

50 240 compounds

Key features

  1. Novel compounds, synthesized within the last 4-5 years
  2. 15 298 clusters in DDS-50
  3. No singletons, 3-6 compounds per cluster
  4. No PAINS, only MedChem-friendly compounds
  5. Express follow-up guaranteed

Molecular properties

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