Acrylamides

The world’s largest collection of Acrylamides

27 943 in stock and over 450 000 in REAL Database

Covalent modifiers have re-emerged as a drug design strategy due to more and more examples of their successful applications and safety. Acrylamides are the most frequently used covalent warheads with proven moderate reactivity and high selectivity to cysteine residue. Our efforts in synthesis of new covalent binders with acrylamide warhead yielded a collection of over 22 400 compounds – the largest source of commercially available acrylamides.

Typical Formats

Catalog No.
Compounds
Amount
Format
Price

Catalog No.

sACR-4160-10-Y-10

Compounds

4 160
13 plates

Amount

10 µL of 10 mM DMSO solutions

Plates and formats

384-well plates Greiner 781280, 320 compounds per plate, first two and last two columns empty

Price

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Catalog No.

fACR-2240-25-Y-100

Compounds

2 240
7 plates

Amount

25 µL of 100 mM DMSO solutions

Plates and formats

384-well plates Greiner 781280, 320 compounds per plate, first two and last two columns empty

Price

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Catalog No.

sACR-4160-50-X-10

Compounds

4 160
52 plates

Amount

50 µL of 10 mM DMSO solutions

Plates and formats

96-well plates, Greiner Cat. No 650201, round (U) bottom, 80 compounds per plate, 1 & 12 columns empty

Price

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Get more details

Download SD files

Acrylamides in stock

27 943 compounds for cherry-picking

 

Plated libraries in stock:

Acrylamide Library

Library code: sACR-4160

Version: 20 February 2023

4 160 compounds

Acrylamide Fragments

Library code: fACR-2240

Version: 10 May 2023

2 240 compounds

Key features

  • Unprecedented Novelty of our acrylamides supported by continuous enrichment with the latest Enamine’s building blocks and unique amines. Over 2 000 new acrylamides are synthesized each year.
  • High Diversity of core structures ensured by careful selection of diverse intermediates possessing variety of chemotypes.
  • Ready-to-use non-overlapping pre-plated sets can be promptly supplied in customized format only within 1-2 weeks:

Representative examples of well-known actives bearing acrylamide moiety and similar structures from Enamine’s in-stock Acrylamides:

All compounds are 90%+ pure (LCMS and/or NMR analysis) and can be delivered as dry powders or in any customized plated formats. Identified hits can be readily re-synthesized and followed with analogs in stock or fast parallel synthesis within only 3 weeks.

You can acquire new compounds from our pool of 450 000 REAL acrylamides. Synthesis takes only 3-4 weeks yielding over 80% of the selected compounds.

Link on the SD file with almost 0.5 M of new Acrylamides accessible within only 3-4 weeks.

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