High-quality diverse library of latest compounds
10 240 compounds
The success of high throughput screening in finding decent starting points for drug discovery heavily depends on the quality of the compound library. Compound screening libraries nowadays must bear an essential degree of novelty, possess contemporary lead-like properties and be built on “live” chemistry that can supply related chemical entities.
Only within last three years Enamine synthesized over 790 000 screening compounds for its public catalog. These substances feature a new structural diversity of Enamine unique building blocks and scaffolds. Having the largest commercial screening collection in the world, Enamine remains the only library producer that keeps enhancing its collection with significant number of new compounds each year. The renowned quality of compounds has been distilled in the design of two Discovery Diversity Sets (DDS). Discovery Diversity Sets are based only on the lead-like compounds including representatives of all three screening collections of Enamine – HTS, Advanced, and Premium.
The Discovery Diversity Sets are highly recommended for random screening against new as well as popular targets because of diversity of scaffolds and presence of latest building blocks.
Discovery Diversity Sets have been plated at 10 mM concentration in DMSO and can be swiftly supplied in different customized formats including following most popular options:
Typical Formats
Catalog No.
DDS-10-0-Z-0
Compounds
10 240
8 plates
Amount
≤ 150 nL of DMSO solutions
Plates and formats
1536-well echo-qualified assay ready microplates, Labcyte LP0400
Catalog No.
DDS-10-10-Y-10
Compounds
10 240
32 plates
Amount
10 µL of 10 mM of DMSO solutions
Plates and formats
384-well acoustic plates, Labcyte LP0200, first and last columns empty, 320 compounds per plate
Catalog No.
DDS-10-50-X-10
Compounds
10 240
128 plates
Amount
50 µL of 10 mM of DMSO solutions
Plates and formats
96-well plates, Greiner Cat. No 650201, round (U) bottom, 1 & 12 columns empty, 80 compounds per plate
Catalog No.
DDS-10
Compounds
10 240
Amount
Custom
Plates and formats
Any custom format
Download SD files
The hits discovered from Discovery Diversity Sets are expected to easily yield lead compounds. All identified hits can be readily followed with analogues either from stock or from new syntheses through our REAL database technology. All building blocks for lead optimization programs are readily available from Enamine stock.
Key features
- Novel compounds
- No PAINS, only medchem friendly compounds
- Express follow-up guaranteed
Comparative analysis of DDSs and commercially available compounds
74% of the compounds from DDS 10K are available exclusively at Enamine
Examples of the molecules
Molecular properties
