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High-quality diverse library of latest compounds

10 240 compounds

The success of high throughput screening in finding decent starting points for drug discovery heavily depends on the quality of the compound library. Compound screening libraries nowadays must bear an essential degree of novelty, possess contemporary lead-like properties and be built on “live” chemistry that can supply related chemical entities.

Only within last three years Enamine synthesized over 790 000 screening compounds for its public catalog. These substances feature a new structural diversity of Enamine unique building blocks and scaffolds. Having the largest commercial screening collection in the world, Enamine remains the only library producer that keeps enhancing its collection with significant number of new compounds each year. The renowned quality of compounds has been distilled in the design of two Discovery Diversity Sets (DDS). Discovery Diversity Sets are based only on the lead-like compounds including representatives of all three screening collections of Enamine – HTS, Advanced, and Premium.

The Discovery Diversity Sets are highly recommended for random screening against new as well as popular targets because of diversity of scaffolds and presence of latest building blocks.

Discovery Diversity Sets have been plated at 10 mM concentration in DMSO and can be swiftly supplied in different customized formats including following most popular options:

Typical Formats

Discovery Diversity Set is available for supply in various pre-plated formats, including the following most popular ones:

Catalog No.
Compounds
Amount
Format
Price

Catalog No.

DDS-10-0-Z-10

Compounds

10 240
8 plates

Amount

≤ 300 nL of 10 mM of DMSO solutions

Plates and formats

1536-well Echo LDV microplates, first and last four columns empty, 1280 compounds per plate

Price

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Catalog No.

DDS-10-10-Y-10

Compounds

10 240
32 plates

Amount

≤ 10 µL of 10 mM DMSO solutions

Plates and formats

384-well, Echo Qualified LDV microplates #001-12782 (LP-0200), first and last two columns empty, 320 compounds per plate

Price

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Catalog No.

DDS-10-50-Y-10

Compounds

10 240
32 plates

Amount

50 μL of 10 mM DMSO solutions

Plates and formats

384-well, Greiner Bio-One plates #781280, 1,2 and 23,24 columns empty, 320 compounds per plate

Price

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*We will be happy to provide our library in any other most convenient for your project format. Please select among the following our standard microplates: Greiner Bio-One 781270, 784201, 781280, 651201 or Echo Qualified 001-12782 (LP-0200), 001-14555 (PP-0200), 001-6969 (LP-0400), C52621 or send your preferred labware. Compounds pooling can be provided upon request.

Download SD files

Discovery Diversity Set

Library code: DDS-10

Version: 30 January 2024

10 240 compounds

The hits discovered from Discovery Diversity Sets are expected to easily yield lead compounds. All identified hits can be readily followed with analogues either from stock or from new syntheses through our REAL database technology. All building blocks for lead optimization programs are readily available from Enamine stock.

Key features

  • Novel compounds
  • No PAINS, only medchem friendly compounds
  • Express follow-up guaranteed

Comparative analysis of DDSs and commercially available compounds

74% of the compounds from DDS 10K are available exclusively at Enamine

Examples of the molecules

Molecular properties

 

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