Publications

A Beckmann rearrangement initiated by trifluoromethanesulfonic anhydride in the synthesis of compounds containing a new pyrazolo[3',4':5,6]pyrido[3,2-b]azepine heterocyclic system

Chem. Heterocycl. Compd. 2021, 57 (2), 199-206

DOI: 10.1007/s10593-021-02893-8

Yakovenko G.; Yagodkina-Yakovenko M.; Suykov S.; Vovk M.
A multi-pronged approach targeting SARS-CoV-2 proteins using ultra-large virtual screening

iScience 2021, 24 (2), 102021

DOI: 10.1016/j.isci.2020.102021

Gorgulla C.; Padmanabha Das K.; Leigh K.; Cespugli M.; Fischer P.; Wang Z.; Tesseyre G.; Pandita S.; Shnapir A.; Calderaio A.; Gechev M.; Rose A.; Lewis N.; et al.
Versatile Reactivity of Mn(II) Complexes in Reactions with N-Donor Heterocycles: Metamorphosis of Labile Homometallic Pivalates vs. Assembling of Endurable Heterometallic Acetates

Molecules 2021, 26 (4), 1021

DOI: 10.3390/molecules26041021

Polunin R.; Evstifeev I.; Cador O.; Golhen S.; Gavrilenko K.; Lytvynenko A.; Efimov N.; Minin V.; Bogomyakov A.; Ouahab L.; Kolotilov S.; Kiskin M.; Eremenko I.
Effect of Charge Distribution in a Modified tRNA Substrate on Pre-Reaction Protein-tRNA Complex Geometry

ACS Omega 2021, 6 (6), 4227-4235

DOI: 10.1021/acsomega.0c05143

Rayevsky A.; Sharifi M.; Demianenko E.; Volochnyuk D.; Tukalo M.
Synthesis of Furoneoflavones Modified by Coumarin and (HET)Aroyl Substituents

Chem. Nat. Compd. 2021, 57 (1), 33-37

DOI: 10.1007/s10600-021-03275-4

Shokol T.; Moskvina V.; Hlibov Y.; Frasinyuk M.; Khilya V.
Efficient Route for the Synthesis of Diverse Heteroannelated 5-Cyanopyridines

Synthesis 2021, 53 (12), 2133-2141

DOI: 10.1055/a-1360-9852

Mityuk A.; Hrebonkin A.; Lebed P.; Grabchuk G.; Volochnyuk D.; Ryabukhin S.
Fluoroalkyl-Containing 1,2-Disubstituted Cyclobutanes: Advanced Building Blocks for Medicinal Chemistry

Eur. J. Org. Chem. 2021, 2021 (1), 87-95

DOI: 10.1002/ejoc.202001345

Demchuk O.; Hryshchuk O.; Vashchenko B.; Trofymchuk S.; Melnykov K.; Skreminskiy A.; Volochnyuk D.; Grygorenko O.
Citraconic acid and its anhydride-based hetero-Diels–Alder reactions in the synthesis of new thiopyrano[2,3-d][1,3]thiazole derivatives

Synth. Commun. 2021, 51 (6), 964-970

DOI: 10.1080/00397911.2020.1867868

Zelisko N.; Karpenko O.; Muzychenko V.; Gzella A.; Lesyk R.
Cyclosulfenylation of N-(1(2)-naphthyl) styrylacetamides as a synthetic route to 4(2)-arylthio naphtho[1,2-b]([2,1-b])azepin-2(4)-ones

J. Sulphur Chem. 2021, 42 (3), 264-280

DOI: 10.1080/17415993.2020.1855431

Danyliuk I.; Vaskevych A.; Vaskevych R.; Rusanov E.; Vovk M.
Synthesis of 4-heteryl-substituted derivatives of methylpyrazolo[1,5-a]pyrazine-4-carboxylates

Chem. Heterocycl. Compd. 2020, 56 (12), 1554-1559

DOI: 10.1007/s10593-020-02849-4

Tsizorik N.; Hrynyshyn Y.; Musiychuk A.; Bol’but A.; Nechayev M.; Vovk M.
Fluorinated Pyrazoles: From Synthesis to Applications

Chem. Rev. 2021, 121 (3), 1670–1715

DOI: 10.1021/acs.chemrev.0c01015

Mykhailiuk P.
Chemography: Searching for Hidden Treasures

J. Chem. Inf. Model. 2021, 61 (1), 179-188

DOI: 10.1021/acs.jcim.0c00936

Zabolotna Y.; Lin A.; Horvath D.; Marcou G.; Volochnyuk D.; Varnek A.
Pharmacological inhibition of syntenin PDZ2 domain impairs breast cancer cell activities and exosome loading with syndecan and EpCAM cargo

J. Extracell. Vesicles 2020, 10 (2), e12039

DOI: 10.1002/jev2.12039

Leblanc R.; Kashyap R.; Barral K.; Egea-Jimenez A. L.; Kovalskyy D.; Feracci M.; Garcia M.; Derviaux C.; Betzi S.; Ghossoub R.; Platonov M.; Roche P.; Morelli X.; Hoffer L.; Zimmermann P.
Synthesis of α-spirocyclic pyrrolidines

Chem. Heterocycl. Compd. 2020, 56 (11), 1411-1413

DOI: 10.1007/s10593-020-02829-8

Melnykov K.; Ryabukhin S.
Exploration of the nitrogen heterocyclic periphery around the core of the advanced FFA1 agonist fasiglifam (TAK-875)

Arch. Pharm. 2021, 354 (4), e2000275

DOI: 10.1002/ardp.202000275

Lukin A.; Bakholdina A.; Zhurilo N.; Onopchenko O.; Zhuravel E.; Zozulya S.; Gureev M.; Safrygin A.; Krasavin M.
[3-(Dimethylamino)-2-(trifluoromethyl)prop-2-en-1-ylidene]dimethylazanium hexafluorophosphate – efficient reagent for the formation of trifluoromethyl-substituted azaheterocycles

Chem. Heterocycl. Compd. 2020, 56 (11), 1408-1410

DOI: 10.1007/s10593-020-02828-9

Mityuk A.; Ryabukhin S.
Modern Approaches to the Creation of Immobilized Metal-Complex Catalysts for Hydrogenation, Alkene Metathesis, and Cross-Coupling Processes: A Review

Theor. Exp. Chem. 2020, 56 (5), 283-308

DOI: 10.1007/s11237-020-09660-4

Ivanytsya M.; Ryabukhin S.; Volochnyuk D.; Kolotilov S.
Bicyclic Piperidines via [2 + 2] Photocycloaddition

J. Org. Chem. 2021, 86 (3), 2200-2209

DOI: 10.1021/acs.joc.0c02355

Shcherbakova V.; Dibchak D.; Snisarenko M.; Skalenko Y.; Denisenko A.; Kuznetsova A.; Mykhailiuk P.
Enantiomeric N-tert-Butylsulfinyl Imines of Methyl Trifluoropyruvate: Promising Building Blocks in Asymmetric Synthesis of α-Trifluoromethylated Amino Acids and Derivatives

ChemistrySelect 2020, 5 (43), 13569-13574

DOI: 10.1002/slct.202003500

Cherednichenko A.; Bezgubenko L.; Rusanov E.; Onys'ko P.; Rassukana Y.
Efficient synthesis of imidazole and pyrimidine derivatives

Chem. Heterocycl. Compd. 2020, 56 (10), 1329-1334

DOI: 10.1007/s10593-020-02818-x

Kolomoitsev O.; Gladkov E.; Kotlyar V.; Pedan P.; Onipko O.; Buravov O.; Chebanov V.
Reaction of N,N-Disubstituted Polyfluoroalkanethioamides with Diazomethane: Entry to New Thiirane Derivatives

Eur. J. Org. Chem. 2021, 2021 (47), 6524-6529

DOI: 10.1002/ejoc.202001104

Shermolovich Y.; Khyzhan A.; Rusanov E.; Mazepa A.; Rakipov I.; Mykhaylychenko S.
SAVI, in silico generation of billions of easily synthesizable compounds through expert-system type rules

Scientific Data 2020, 7 (1), 384

DOI: 10.1038/s41597-020-00727-4

Patel H.; Ihlenfeldt W.; Judson P.; Moroz Y.; Pevzner Y.; Peach M.; Delannee V.; Tarasova N.; Nicklaus M.
Small-Molecule Chemical Knockdown of MuRF1 in Melanoma Bearing Mice Attenuates Tumor Cachexia Associated Myopathy

Cells 2020, 9 (10), 2272

DOI: 10.3390/cells9102272

Adams V.; Gussen V.; Zozulya S.; Cruz A.; Moriscot A.; Linke A.; Labeit S.
Composites Based on Nanodispersed Nickel, Graphene-Like Carbon, and Aerosil for Catalytic Hydrogenation of Furfural and Quinoline

Theor. Exp. Chem. 2020, 56 (4), 261-267

DOI: 110.1007/s11237-020-09657-z

Asaula V.; Shvets O.; Pariiska O.; Bur’yanov V.; Ryabukhin S.; Volochnyuk D.; Kolotilov S.
An efficient method for accessing carboannulated and functionalized [1,2,3]triazolo[4,5-b]pyridines

Chem. Heterocycl. Compd. 2020, 56 (8), 1048‑1053

DOI: 10.1007/s10593-020-02771-9

Syrota N.; Kemskiy S.; Bol’but A.; Chernobaev I.; Vovk M.
Chan-Evans-Lam N1-(het)arylation and N1-alksmall ie, Cyrillicnylation of 4-fluoroalkylpyrimidin-2(1H)-ones

Beilstein J. Org. Chem. 2020, 16, 2304-2313

DOI: 10.3762/bjoc.16.191

Tkachuk V.; Lukianov O.; Vovk M.; Gillaizeau I.; Sukach V.
2,2,2-Trifluorodiazoethane (CF3CHN2): A Long Journey since 1943

Chem. Rev. 2020, 120 (22), 12718-12755

DOI: 10.1021/acs.chemrev.0c00406

Mykhailiuk P.
Practical synthetic method for functionalized 1-methyl-3/5-(trifluoromethyl)-1H-pyrazoles

Org. Process Res. Dev. 2020, 24 (11), 2619‑2632

DOI: 10.1021/acs.oprd.0c00300

Tairov M.; Levchenko V.; Stadniy I.; Dmytriv Y.; Dehtiarov S.; Kibalnyi M.; Melnyk A.; Veselovych S.; Borodulin Y.; Kolotilov S.; Ryabukhin S.; Volochnyuk D.
Diarylethene moiety as an enthalpy-entropy switch: photoisomerizable stapled peptides for modulating p53/MDM2 interaction

Org. Biomol. Chem. 2020, 18 (28), 5359-5369

DOI: 10.1039/d0ob00831a

Strizhak A.; Babii O.; Afonin S.; Bakanovich I.; Pantelejevs T.; Xu W.; Fowler E.; Eapen R.; Sharma K.; Platonov M.; Hurmach V.; Itzhaki L.; Hyvonen M.; Ulrich A.; Spring D.; Komarov I.
Photoregulated macrocyclic cell-penetrating peptides

Chem. Heterocycl. Compd. 2020, 56 (6), 719-721

DOI: 10.1007/s10593-020-02721-5

Komarov I.; Bakanovych I.
Saturated Bioisosteres of ortho-Substituted Benzenes

Angew. Chem. Int. Ed. 2020, 59 (46), 20515‑20521

DOI: 10.1002/anie.202004183

Denisenko A.; Garbuz P.; Shishkina S.; Voloshchuk N.; Mykhailiuk P.
Peptidyl inhibition of Spt4-Spt5: Protein-protein inhibitors for targeting the transcriptional pathway related to C9orf72 expansion repeats

J. Cell. Biochem. 2020, 121 (12), 4922-4930

DOI: 10.1002/jcb.29820

Rayevsky A.; Platonov M.; Hurmach V.; Yakovenko A.; Volochnyuk D.
Formyl MIDA Boronate: C1 Building Block Enables Straightforward Access to α-Functionalized Organoboron Derivatives

Angew. Chem. Int. Ed. 2020, 59 (41), 18016‑18022

DOI: 10.1002/anie.202007651

Ivon Y.; Mazurenko I.; Kuchkovska Y.; Voitenko Z.; Grygorenko O.
Synthesis of new-type 1,3,6-triazocine via intramolecular reactions of iodocyclization and [3+2] azido cycloaddition

J. Heterocycl. Chem. 2020, 57(8), 3202‑3212

DOI: 10.1002/jhet.4028

Vaskevych R.; Vaskevych A.; Rusanov E.; Mel'nyk O.; Vovk M.
Similarities of Coordination Polymer and Dimeric Complex of Europium(III) with Joint and Separate Terpyridine and Benzoate

Z. Anorg. Allg. Chem. 2020, 646 (20), 1710‑1714

DOI: 10.1002/zaac.201900319

Sedykh A.; Sotnik S.; Kurth D.; Volochnyuk D.; Kolotilov S.; Müller-Buschbaum K.
NMR quality control of fragment libraries for screening

J. Biomol. NMR 2020, 74 (10-11), 555–563

DOI: 10.1007/s10858-020-00327-9

Sreeramulu S.; Richter C.; Kuehn T.; Azzaoui K.; Blommers M.; Del Conte R.; Fragai M.; Trieloff N.; Schmieder P.; Nazare M.; Specker E.; Ivanov V.; Oschkinat H.; Banci L.; Schwalbe H.
Electrochemical Scaled-up Synthesis of Cyclic Enecarbamates as Starting Materials for Medicinal Chemistry Relevant Building Bocks

Advanced Synthesis and Catalysis 2020, 362 (15), 3229-3242

DOI: 10.1002/adsc.202000450

Tereshchenko O.; Perebiynis M.; Knysh I.; Vasylets O.; Sorochenko A.; Slobodyanyuk E.; Rusanov E.; Borysov O.; Kolotilov S.; Ryabukhin S.; Volochnyuk D.
Exploring bulky natural and natural-like periphery in the design of p-(benzyloxy)phenylpropionic acid agonists of free fatty acid receptor 1 (GPR40)

Bioorg. Chem. 2020, 99, 103830

DOI: 10.1016/j.bioorg.2020.103830

Kuranov S.; Luzina O.; Onopchenko O.; Pishel I.; Zozulya S.; Gureev M.; Salakhutdinov N.; Krasavin M.
Synthesis of 4,4-Disubstituted 1,2-Thiazinane-5-one 1,1-Dioxides via the CSIC[≠] Reaction Strategy

ChemistrySelect 2020, 5 (19), 5573-5576

DOI: 10.1002/slct.202001243

Dyachenko M.; Kochetkov A.; Dobrydnev A.; Milokhov D.; Shishkina S.; Konovalova I.; Omelchenko I.; Volovenko Y.
Fluoral Hydrate: A Perspective Substrate for the Castagnoli-Cushman Reaction

ACS Omega 2020, 5 (33), 20932-20942

DOI: 10.1021/acsomega.0c02394

Adamovskyi M.; Avramenko M.; Volochnyuk D.; Ryabukhin S.
Fluoroalkyl-Substituted Cyclopropane Derivatives: Synthesis and Physicochemical Properties

J. Org. Chem. 2020, 85 (19), 12692-12702

DOI: 10.1021/acs.joc.0c01848

Chernykh A.; Olifir O.; Kuchkovska Y.; Volochnyuk D.; Yarmolchuk V.; Grygorenko O.
Reactions of cyclic β-alkoxyvinyl α-keto esters with heteroaromatic NCC-binucleophiles

Chem. Heterocycl. Compd. 2020, 56 (3), 377–385

DOI: 10.1007/s10593-020-02670-z

Stepaniuk O.; Vashchenko B.; Matvienko V.; Kondratov I.; Tolmachev A.; Grygorenko O.
Synthesis of functionalized bridged bicyclic sulfonamides with a bridgehead Nitrogen atom

Eur. J. Org. Chem. 2020, 2020 (22), 3261-3269

DOI: 10.1002/ejoc.202000314

Blahun O.; Melnychenko H.; Kuchkovska Y.; Zhersh S.; Tolmachev A.; Grygorenko O.
Synthesis and oxidation of all isomeric 2-(pyrazolyl)ethanols

Chem. Heterocycl. Compd. 2020, 56 (3), 320-325

DOI: 10.1007/s10593-020-02662-z

Ivonin S.; Rusanov E. B.; Dmitriy V.
Synthesis of 5-amino-1H-pyrazolo[4,3-b]pyridine derivatives and annulation of imidazole and pyrimidine rings thereto

Chem. Heterocycl. Compd. 2020, 56 (3), 347-354

DOI: 10.1007/s10593-020-02666-9

Yakovenko G.; Lukianov O.; Yagodkina-Yakovenko M.; Bol’but A.; Vovk M.
A convenient approach to 3-trifluoromethyl-6-azaindoles

J. Fluorine Chem. 2020, 233

DOI: 10.1016/j.jfluchem.2020.109509

Ivonin S.; Yurchenko A.; Voloshchuk V.; Yurchenko S.; Rusanov E.; Pirozhenko V.; Volochnyuk D.; Kostyuk A.
Synthesis, biological evaluation, and modeling studies of 1,3-disubstituted cyclobutane-containing analogs of combretastatin A4

J. Mol. Struct. 2020, 1210

DOI: 10.1016/j.molstruc.2020.128025

Malashchuk A.; Chernykh A.; Hurmach V.; Platonov M.; Onopchenko O.; Zozulya S.; Daniliuc C.; Dobrydnev A.; Kondratov I.; Moroz Y.; Grygorenko O.
An unexpected synthesis of β-amino-α-mesyl-γ-sultams upon mesylation of hindered α-aminonitriles

Chem. Heterocycl. Compd. 2020, 56 (3), 386–391

DOI: 10.1007/s10593-020-02671-y

Dyachenko M.; Dobrydnev A.; Chuchvera Y.; Shishkina S.; Volovenko Y.
gem-Difluorocyclopropanation of Alkenyl Trifluoroborates with the CF3SiMe3-NaI System

Eur. J. Org. Chem. 2020, (15), 2217-2224

DOI: 10.1002/ejoc.202000346

Hryshchuk O.; Varenyk A.; Yurov Y.; Kuchkovska Y.; Tymtsunik A.; Grygorenko O.
Photochemical [2 + 2] cycloaddition of alkenyl boronic derivatives: an entry into 3-azabicyclo[3.2.0]heptane scaffold

J. Org. Chem. 2020, 85 (9), 5927-5940

DOI: 10.1021/acs.joc.0c00265

Demchuk O.; Hryshchuk O.; Vashchenko B.; Kozytskiy A.; Tymtsunik A.; Komarov I.; Grygorenko O.

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