News

We are excited to share some news about the strategic partnership between Enamine and Genez International.

We understand the challenges that scientists face while navigating through huge chemical spaces. Our task is to simplify and streamline this process.

Please welcome a new access point to Enamine REAL Space and Chemspace Freedom Space 3.0 – Hyperspace! It is a fantastic search tool created by our partners from Alipheron.

We are excited to announce a strategic collaboration between Enamine, the world's leading provider of chemical building blocks, compound libraries, and biology services, and Genez International, a prominent enterprise with 15 years of experience in cross-border supply management, biopharmaceutical research and development, semiconductor equipment, and high-definition digital imaging systems.

This morning, russia carried out another act of aggression, firing dozens of rockets at peaceful cities in Ukraine, including Kyiv. Another act of barbarian terrorism. Despite it, we stand firm and resilient.

We are excited to co-author a new article published in the journal Science: “Structure-based discovery of nonopioid analgesics acting through the α2A-adrenergic receptor”, resulting from a fruitful international collaboration involving:

We are glad to inform you that we have fully restored the scope of our building block catalog as it was before the 24^th of February war outbreak. The catalog lists over 238 000 off-the-shelf products. Such items are again offered in the various batch sizes reaching up to 100 grams in many cases to give you full scale of choice for your projects. Please visit https://enaminestore.com/catalog to make structure searches and order online.

Since our return to the labs 1 month ago, we have managed to restore and catch up with practically all our synthesis and stock operations. We are extremely grateful for your being with us during these difficult times. We were happy to receive your messages of strong support and orders, demonstrating your continuous trust in Enamine. It means a lot to all of us, and it helped our quick rebirth.

Now more than 400 chemists have returned to our labs, among whom 150 as FTE’s in your research projects. Each week more chemists join back their FTE team structures. In early 2022, the company made a strategic supply of reagents and solvents so that we can continue self-sufficient synthesis activities for many months. Furthermore, most recently, significant progress has been made in receiving again goods and starting materials in Ukraine. Our newly established small synthesis lab in Latvia operates now in parallel to the Kyiv-based ones and will be happy to welcome new FTE clients.

Our parallel synthesis lab is capable now of setting up 1 400 - 1 500 syntheses per day, the rate that allows the synthesis of a few thousand REAL Compounds in a 2-month project. There is no limitation to the library size to request. As we used to encounter difficulties in dealing with the end-of-the-year REAL Compound orders always arriving in numbers, we would like to encourage you to send your requests as soon as possible and book our optimally available capacities in advance!

Enamine chemists back on creative spree. A few latest additions to our Building Block catalog

Enamine has resumed internal synthesis programs targeting to replenish and expand our catalog of Building Blocks. The strategic goal is to replicate our stock of BBs and make it evenly represented in all our three warehouses: in the US, in Latvia, and in Ukraine. The first step in this direction was made when we shipped sizeable selections of building blocks to our stocks abroad. Now our chemists are busy in resynthesizing them.

All our stock catalogs including building blocks, screening compounds, fragments, and plated compound libraries are readily available for your analysis and fully operatable. Our delivery times improve every week!

We are happy to inform you that we have successfully completed the relocation of our entire collection of screening compounds and started weighing compound samples since yesterday. All 3.5 million vials with dry compounds have been safely moved to our new facility in Sokal, a town near Lviv with a population of 20 000 people in the West of Ukraine, close to the Polish border.

As of today, 17 countries among which France, Italy, and Austria to name a few, along with the European Union have sent their diplomats back to Kyiv, reopening their embassies, a vote of confidence that the Russia’s assault against the Ukrainian capital city and its region is over. This important symbolic and solidarity step from our allies makes clear that the necessary safety in Kyiv is returning, while the Russians have decided to re-focus on the East of Ukraine.

From our side, we are continuing working at full throttle to contribute to restoring our beloved homeland and its economy. Over 350 chemists including 100 FTE’s in our clients’ research projects have been able to resume their programs in our laboratories in Kyiv. We appreciate tremendously your indefatigable support, commitment, and trust in us!

This week we are happy to announce that our compound management team has resumed the liquid handling replication of our compound libraries. Although some more time (2 weeks) is required to fully re-start the weighing of dry compound samples from our screening collection, we can already supply from our liquid stock various pre-plated compound libraries. In line with our last week’s announcement, our very first dry-ice shipment since nearly two months has just left Kyiv towards our logistics centre in Riga from where individual orders will be further distributed to multiple clients across the world.

We are also pleased to confirm that our biology department Bienta has fully resumed its operations and provision of integrated drug discovery support. All our research facilities and technical equipment are in perfect working condition. Currently, all our groups and units (high throughput screening, bioanalytical, mass spectrometry, and in vivo) are resuming their projects and are ready to start new ones. The in vivo group is restoring the population of its laboratory animals, which were saved in our in-house core breeding section thanks to our galvanized colleagues’ efforts.

For further details, please send inquiries to This email address is being protected from spambots. You need JavaScript enabled to view it..

Faithfully Yours,
Enamine Team

The situation in Kyiv keeps improving day by day, shops and restaurants are re-opening and people are returning to their homes in a continuous stream. More and more chemists come back to their labs and resume their projects at Enamine. Currently, over 300 chemists are already back to work, and we estimate this number to grow up to 400-500 colleagues within the next couple of weeks. We have restored the synthesis of building blocks, REAL Compounds, as well as custom synthesis, including FTE research projects in our Kyiv’s facility. Along with our absolute capacity to resynthesize building blocks in larger amounts as before, the resumption of the supplies from Ukraine has allowed us to return 2.5-, 5-, and 10-gram amounts to our building block catalog. Following our contingency plan at the war outbreak, we completely switched to supplies from our warehouses in US and Latvia, both largely limited to the 1-gram batch size. Now, we are resuming supplies of the larger amounts from our Kyiv stock and via resynthesis! Please check our offer at https://enaminestore.com/.

The quick supply of the building blocks is crucial. Even though the infrastructure in Ukraine has been significantly damaged during the war and despite express courier services have been suspended for the time being, our logistics specialists have organized a 3-day ground transportation route from Kyiv to our EU-based site in Latvia. This means that delivery time from Ukraine to your lab will be cut down to around 7-10 days very soon. Delivery time from US and EU local stores is as always 1-2 days.

We are looking forward to receiving your new inquiries and orders! This is the best way you can help us.

Faithfully Yours,
Enamine Team

We, at Enamine, have united to resist at our level the Russian invasion. We help to acquire non-lethal military aid to enhance defence of Ukraine, provide medical supplies to the hospitals, provide sponsorship for science and education in Ukraine, and help our employees scattered by war across Ukraine and abroad. Our own funds are limited as we have had to put on hold most of our projects and we will greatly appreciate your donations, which we will immediately use for the urgent needs of today! This is the most direct help to Ukraine.

Please use correct currency accounts and indicate the purpose of payment as “charitable assistance”.

In order to track your donation please inform us about it by email: This email address is being protected from spambots. You need JavaScript enabled to view it.. If you have any particular purpose of donation (e.g. “medicines”, “social help”) please indicate it in your email. Please also contact us by email if you have any questions about the fund.

Thank you for your support!

A group of scientists led by Qubit cooperated on computer-driven de novo design of potential active molecules, with the subsequent synthesis of the most promising inhibitors by Enamine and their in vitro activity testing at Università degli Studi di Padova.

We are proud to announce that our covalent compound library is now available in a ready-to-dock format for BioSolveIT’s drug design dashboard SeeSAR. Over 20 different warheads were processed and translated to their respective ligand-bound form to assess their binding mode after docking.

Please join us for a webinar "Hit Discovery for GPCRs: HTS or Virtual Screens?” presented by Guest Speaker, Carleton Sage, PhD, Vice President of Computational Sciences at Eurofins, Beacon Discovery on Thursday, June 24, 2021

We still have several funded Postdoc positions in organic chemistry to work at Enamine Ltd. (Ukraine, Kyiv) on a ERC-project “Saturated bioisosteres of benzene.”

Start: any time.
Please, send the application documents (motivation letter, CV, list of publications, recommendation letters) to This email address is being protected from spambots. You need JavaScript enabled to view it.

We are happy to announce the start of Project ALISE supported by European Commission under Horizon 2020 MSCA-RISE. As the coordinator of the Project, Enamine is involved in the development of light-controllable antibody peptide conjugates pushing the boundaries of photopharmacology towards clinical applications.

We have several Postdoc positions in organic chemistry to work at Enamine Ltd. (Ukraine, Kyiv) on a ERC-project “Saturated bioisosteres of benzene.” Start: 1 April 2021 (or later).

Please, send the application documents (motivation letter, CV, list of publications, recommendation letters) to This email address is being protected from spambots. You need JavaScript enabled to view it.

Congratulations to Pavel Mykhailiuk, Chief Scientific Officer at Enamine, for receiving ERC Consolidator Grant funding for the Project: BENOVELTY - Saturated bioisosteres of benzene and their application in drug design.

The research will be carried out at Enamine Ltd in Ukraine, a global provider of chemical and biological services to biotech companies, academic institutions and research organisations.

Enamine will provide chemical synthesis support for a global nonprofit research initiative OpenPandemics COVID-19, organized by Scripps Research and IBM, and aimed at rapidly identifying efficient new drugs against the coronavirus SARS-CoV-2. Enamine will be synthesizing any promising hits identified by the research team at OpenPandemics COVID-19 via large scale docking experiments.

An international group of scientists from academia and industry, including Enamine, is trying to help combat COVID-19. This effort began when Chinese scientists worked rapidly to determine the structure of the novel SARS‑CoV‑2 main protease (M^pro), which triggered a massive crystal-based fragment screen at the XChem facility at UK’s Diamond Light Source. For more details, please visit https://www.diamond.ac.uk/covid-19. With the same urgency, the scientists are now trying to progress these data towards what is desperately needed: effective, easy-to-make anti-COVID drugs https://covid.postera.ai/covid.