Discovery Diversity Set - 10

High-quality diverse library of latest compounds

10 240 compounds

The success of high throughput screening in finding decent starting points for drug discovery heavily depends on the quality of the compound library. Compound screening libraries nowadays must bear an essential degree of novelty, possess contemporary lead-like properties and be built on “live” chemistry that can supply related chemical entities.

 

Only within last three years Enamine synthesized over 790 000 screening compounds for its public catalog. These substances feature a new structural diversity of Enamine unique building blocks and scaffolds. Having the largest commercial screening collection in the world, Enamine remains the only library producer that keeps enhancing its collection with significant number of new compounds each year. The renowned quality of compounds has been distilled in the design of two Discovery Diversity Sets (DDS). Discovery Diversity Sets are based only on the lead-like compounds including representatives of all three screening collections of Enamine – HTS, Advanced, and Premium.

 

The Discovery Diversity Sets are highly recommended for random screening against new as well as popular targets because of diversity of scaffolds and presence of latest building blocks.

 

Discovery Diversity Sets have been plated at 10 mM concentration in DMSO and can be swiftly supplied in different customized formats including following most popular options:

Typical Formats

Catalog No.
Compounds
Amount
Format

Catalog No.

DDS-10-0-Z-0

Compounds

10 240
8 plates

Amount

≤ 150 nL of DMSO solutions

Plates and formats

1536-well echo-qualified assay ready microplates, Labcyte LP0400

Catalog No.

DDS-10-10-Y-10

Compounds

10 240
32 plates

Amount

10 µL of 10 mM of DMSO solutions

Plates and formats

384-well acoustic plates, Labcyte LP0200, first and last columns empty, 320 compounds per plate

Catalog No.

DDS-10-50-X-10

Compounds

10 240
128 plates

Amount

50 µL of 10 mM of DMSO solutions

Plates and formats

96-well plates, Greiner Cat. No 650201, round (U) bottom, 1 & 12 columns empty, 80 compounds per plate

Catalog No.

DDS-10

Compounds

10 240

Amount

Custom

Plates and formats

Any custom format

 

Get more details

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Discovery Diversity Set

Library code: DDS-10

Version: 30 January 2024

10 240 compounds

The hits discovered from Discovery Diversity Sets are expected to easily yield lead compounds. All identified hits can be readily followed with analogues either from stock or from new syntheses through our REAL database technology. All building blocks for lead optimization programs are readily available from Enamine stock.

Key features

  • Novel compounds
  • No PAINS, only medchem friendly compounds
  • Express follow-up guaranteed

Comparative analysis of DDSs and commercially available compounds

74% of the compounds from DDS 10K are available exclusively at Enamine

Examples of the molecules

 

Molecular properties

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