Among recurring drug motifs, 2-substituted 5-CF₃-pyridine is extremely common, enabling a broad spectrum of interactions within protein pockets. To incorporate this fragment, the 2-chloro derivative is widely used, making 2-Cl-5-CF₃-pyridine one of the popular building blocks in modern medicinal chemistry research. At Enamine, we have prepared an extensive library of analogues of this compound, ready to diversify your compound collections.
Case studies
Download SD files
Download PDF file
We offer
Over 100 analogues of 5-CF₃-2-Cl-pyridine from stock on 5-10 gram scale.
