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Synthesis of novel 1,2-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one derivatives

Tetrahedron Lett. 2018, 59 (5), 442-444

DOI: 10.1016/j.tetlet.2017.12.065

Yaremchuk I.; Muzychka L.; Smolii O.; Kucher O.; Shishkina S.

The iodolactonization product obtained from methyl 7-allylpyrrolo[2,3-d]pyrimidine-6-carboxylate was used for the synthesis of novel 1,2-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one derivatives, containing carboxamide- and methylamine-groups on the pyrrole ring of the heterocycle.

Synthesis of novel 1,2-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one derivatives

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