New Life for Diazoacetonitrile (N2CHCN): in situ Generation and Practical Synthesis of CN-Pyrazoles
Eur. J. Org. Chem. 2015, 33, 7235-7239
Explosive diazoacetonitrile (N2CHCN) was generated in situ and used in the practical synthesis of agrochemistry-related CN-pyrazoles. In situ generated N2CHCN is much safer than the individual reagent. The developed method is, therefore, expected to make this reagent as useful in chemistry as ethyl diazoacetate (N2CHCO2Et).