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Synthesis of imidazo[1,2-a]pyrazine and imidazo[1,2-a]pyrimidine derivatives

Chem. Heterocycl. Compd. , 2013, 49 (5), 704-711

DOI: 10.1007/s10593-013-1301-6

I. A.; Kovalenko S. N.

Synthetic approaches to the construction of bicyclic systems containing the imidazole nucleus have been considered. Methods for obtaining derivatives of imidazo[1,2-a]pyrazine and imidazo[1,2-a]pyrimidine have been studied, and methods have been developed for catalytic hydrogenation of these compounds. Partial reduction of the imidazole ring on imidazo[1,2-a]pyrimidine hydrogenation has been discovered for the first time.

Synthesis of imidazo[1,2-a]pyrazine and imidazo[1,2-a]pyrimidine derivatives

Borisov A. V.; Tolmachev A. A.; Zavada O. A.; Zhuravel’ I. A.; Kovalenko S. N.
Chem. Heterocycl. Compd. 2013, 49 (5), 704-711
DOI: 10.1007/s10593-013-1301-6

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