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Facile Synthesis of Fluorinated 1-Desazapurines

Synthesis , 2009, 11, 1865-1875

DOI: 10.1055/s-0029-1216802

Iaroshenko V. O.; Sevenard D. V.; Volochnyuk D. M.; Wang Y.; Martiloga A.; Tolmachev A. O.

A preparative approach towards 1-desazapurines, starting from 4(5)-aminoimidazoles and polyfluoroalkyl-containing 1,3-CCC-biselectrophiles was developed. As a result, a set of fluorinated 1-desazapurines was synthesized. Additionally, a synthetic route to 1-desazapurines bearing a sugar-mimicking group is proposed.

Facile Synthesis of Fluorinated 1-Desazapurines

Iaroshenko V. O.; Sevenard D. V.; Volochnyuk D. M.; Wang Y.; Martiloga A.; Tolmachev A. O.
Synthesis 2009, 11, 1865-1875
DOI: 10.1055/s-0029-1216802

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