Recyclization of 2-(3,6-diaryl-2,5-dihydropyridazin-4-yl)-1H-benzimidazoles to 2-[(3,5-diarylpyrazol-4-yl)methyl]-1H-benzimidazoles
Chem. Heterocycl. Compd. , 2008, 44 (6), 682-689
2-(3,6-Diaryl-2,5-dihydropyridazin-4-yl)-1H-benzimidazoles undergo a previously unknown type of recyclization of the pyridazine ring to a pyrazole to give 2-[(3,5-diarylpyrazol-4-yl)methyl]-1H-benzimidazoles. It is suggested that the mechanism of this conversion, which includes formation of a secondary enhydrazine group in the diazine ring and its subsequent contraction, occurs after the intramolecular formation and opening of a cyclopropane ring.
Dzvinchuk I. B.; Chernega A. N.; Lozinskii M. O.; Tolmachev A. A.
Chem. Heterocycl. Compd. 2008, 44 (6), 682-689