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Chlorotrimethylsilane-Mediated Friedländer Synthesis of Polysubstituted Quinolines

Synthesis , 2007, 08, 1214-1224

DOI: 10.1055/s-2007-966003

Ryabukhin S. V.; Volochnyuk D. M.; Plaskon A. S.; Naumchik V. S.; Tolmachev A. A.

New convenient conditions for the Friedländer synthesis of quinolines are described. Polysubstituted quinolines were readily prepared using chlorotrimethylsilane as a promoter and water-acceptor agent.

Chlorotrimethylsilane-Mediated Friedländer Synthesis of Polysubstituted Quinolines

Ryabukhin S. V.; Volochnyuk D. M.; Plaskon A. S.; Naumchik V. S.; Tolmachev A. A.
Synthesis 2007, 08, 1214-1224
DOI: 10.1055/s-2007-966003

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