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Synthesis of 5-Amino-4-(4-aryl-2-thiazolyl)-2,3-Dihydro-2-Pyrrolones

Russ. J. Org. Chem. , 2005, 41 (2), 257-260

DOI: 10.1007/s11178-005-0153-7

Resnyanskaya E. V.; Tverdokhlebov A. V.; Tolmachev A. A.; Volovenko Y. M.

A method was developed for preparation of 5-amino-4-(4-aryl-2-thiazolyl)-2,3-dihydro-2-pyrrolones by alkylation of 4-aryl-2-thiazolylacetonitriles by N-substituted chloroacetamides in the presence of K2CO3. In 1-(1-naphthyl)-substituted pyrrolones atropoisomerism was observed.

Synthesis of 5-Amino-4-(4-aryl-2-thiazolyl)-2,3-Dihydro-2-Pyrrolones

Resnyanskaya E. V.; Tverdokhlebov A. V.; Tolmachev A. A.; Volovenko Y. M.
Russ. J. Org. Chem. 2005, 41 (2), 257-260
DOI: 10.1007/s11178-005-0153-7

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