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One-Pot Synthesis of 6-Aminopyrido[2,3-d]pyrimidin-7-ones

Eur. J. Org. Chem. 2018, 46, 6519-6523

DOI: 10.1002/ejoc.201801204

Zinchenko A.; Muzychka L.; Kucher O.; Sadkova I.; Mykhailiuk P.; Smolii O.

One‐pot synthesis of 6‐aminopyrido[2,3‐d]pyrimidin‐7‐ones from 4‐aminopyrimidine‐5‐carbaldehydes and the in situ N‐protected methyl glycinate is developed. The obtained compounds have a polyfunctional character and provide opportunities for their use in drug design projects.

One-Pot Synthesis of 6-Aminopyrido[2,3-d]pyrimidin-7-ones

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