Russ. J. Org. Chem. 2005, 41 (2), 257-260
DOI: 10.1007/s11178-005-0153-7
Resnyanskaya E. V.; Tverdokhlebov A. V.; Tolmachev A. A.; Volovenko Y. M.
A method was developed for preparation of 5-amino-4-(4-aryl-2-thiazolyl)-2,3-dihydro-2-pyrrolones by alkylation of 4-aryl-2-thiazolylacetonitriles by N-substituted chloroacetamides in the presence of K2CO3. In 1-(1-naphthyl)-substituted pyrrolones atropoisomerism was observed.