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J. Org. Chem. 2018, 83 (3), 1394–1401

DOI: 10.1021/acs.joc.7b02910

Druzhenko T.; Skalenko Y.; Samoilenko M.; Denisenko A.; Zozulya S.; Borysko P.; Sokolenko M.; Tarasov A.; Mykhailiuk P.

Intramolecular photochemical [2 + 2]-cyclization of acetophenone enamides gave 2-azabicyclo[3.2.0]heptanes, advanced building blocks for drug discovery. Synthesis of a conformationally restricted analogue of proline, 2,3-ethanoproline, was performed.

Photochemical Synthesis of 2-Azabicyclo[3.2.0]heptanes: Advanced Building Blocks for Drug Discovery. Synthesis of 2,3-Ethanoproline

 

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