Molecules 2019, 24 (7), 1249-1260
DOI: 10.3390/molecules24071249
Sokolenko L.; Orlova R.; Filatov A.; Yagupolskii Y.; Magnier E.; Pegot B.; Diter P.
A simple and efficient protocol for the oxidation of trifluoromethyl, mono- and difluoromethyl sulfides to the corresponding sulfoxides without over-oxidation to sulfones, using TFPAA prepared in situ from trifluoroacetic acid and 15% H2O2 aqueous solution was developed. The methodology is suitable for a wide range of aromatic and aliphatic substrates in milligram and multigram scales.