search
Login Form

Synth. Commun. , 2008, 38 (17), 3032-3043

DOI: 10.1080/00397910802044272

Ryabukhin S. V.; Plaskon A. S.; Volochnyuk D. M.; Pipko S. E.; Tolmachev A. A.

A facile one-pot method for the synthesis of 1,2,3,4-tetrahydroquinoline-3-carboxylic acids and their heterocyclic analogs based on the tert-amino effect. A set of 1,2,3,4-tetrahydroquinoline-3-carboxylic acids was readily prepared starting from various ortho-dialkylaminoaldehydes and Meldrum's acid using Me3SiCl in dimethylformamide (DMF) solution.

Facile One-Pot Synthesis of 1,2,3,4-Tetrahydroquinoline-3-carboxylic Acids and Their Heterocyclic Analogs

Ryabukhin S. V.; Plaskon A. S.; Volochnyuk D. M.; Pipko S. E.; Tolmachev A. A.
Synth. Commun. 2008, 38 (17), 3032-3043
DOI: 10.1080/00397910802044272

 

Contact Us