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Org. Lett. 2019, 21 (22), 8909-8914

DOI: 10.1021/acs.orglett.9b03080

Dibchak D.; Shcherbacova V.; Denisenko A.; Mykhailiuk P.

Synthesis of the previously unknown conformationally rigid sultams fused with the cyclobutane ring was developed. The key transformation was an intramolecular photochemical cyclization of linear sulfonamides. Crystallographic analysis showed that the obtained structures populated the uncharted region in the chemical space.

Convenient Access to Conformationally Rigid Sultams

 

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