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Synthesis , 2007, 12, 1861-1871

DOI: 10.1055/s-2007-983704

Ryabukhin S. V.; Plaskon A. S.; Volochnyuk D. M.; Tolmachev A. A.

The reaction of 3-formylchromones with aminoheterocycles was investigated. A simple and flexible general procedure for annulation of 5-(2-hydroxybenzoyl)pyridines was proposed. The best reaction conditions were found to be heating the reaction mixture in DMF in the presence of Me3SiCl as a promoter and water as scavenger.

Chlorotrimethylsilane-Mediated Synthesis of Functionalized Fused Pyridines: Reaction of 3-Formylchromones with Electron-Rich Aminoheterocycles

Ryabukhin S. V.; Plaskon A. S.; Volochnyuk D. M.; Tolmachev A. A.
Synthesis 2007, 12, 1861-1871
DOI: 10.1055/s-2007-983704

 

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