Org. Lett. 2025, 27 (21), 5318–5323
DOI: 10.1021/acs.orglett.5c00922
Datsenko O.; Baziievskyi A.; Sadkova I.; Campos B.; Brewster J.; Kowalski J. et al.
Alkyl azetidines have been prepared by photochemical modifications of azetidine-2-carboxylic acids in batch and in flow. The reaction has been realized in milligram, gram, and even multigram quantities. The obtained azetidines are valuable building blocks for drug discovery.