Chem. Heterocycl. Compd. 2021, 57 (6), 666-671
DOI: 10.1007/s10593-021-02965-9
Petko K.; Filatov A.
The addition reaction of perfluoromethyl vinyl ether to various azoles – derivatives of pyrrole, imidazole, pyrazole, indole, benzotriazole, carbazole, and triazole has been demonstrated. The reaction conditions depended both on melting point and nucleophilicity of the heterocycle. The obtained products are hydrolytically and thermally stable, have highly lipophilic moiety and can serve as useful precursors in different synthesis of bioactive compounds.