Synthesis of Fluorinated Oxazoles by Oxidative Cyclization of Fluorinated Enamides
J. Fluorine Chem. 2017, 196, 88-97
DOI: 10.1016/j.jfluchem.2016.09.014
Shishlyk O.; Shcherbatiuk A.; Iminov R.; Tverdokhlebov A.; Tolmachev A.; Mykhailiuk P.; Biitseva A.
Novel approach to CF3-/CHF2-oxazoles was developed. The key reaction was oxidation of fluoroalkyl enamides with PhI(RCO2)2.
