A Facile Synthesis of N-Carbamoylamino Acids
Synlett , 2008, 15, 2279-2282
DOI: 10.1055/s-2008-1078017
Bogolubsky A. V.; Ryabukhin S. V.; Pakhomov G. G.; Ostapchuk E. N.; Shivanyuk A. N.; Tolmachev A. A.
N-Carbamoylamino acids were obtained through the alkylation of monosubstituted parabanic acids followed by hydrolysis of the intermediate products. This new methodology furnishes structurally and functionally diverse N-carbamoylamino acids in high preparative yields and excellent purity.
Bogolubsky A. V.; Ryabukhin S. V.; Pakhomov G. G.; Ostapchuk E. N.; Shivanyuk A. N.; Tolmachev A. A.
Synlett 2008, 15, 2279-2282
DOI: 10.1055/s-2008-1078017