Nanoencapsulation of Calix[4]arene Inclusion Complexes

A hexameric resorcinarene nanocapsule in wet CDCl₃ forms inclusion complexes of calix[4]arene with tetramethylammonium and trimethylsulfoxonium cations to give highly stable Russian-doll-type multicomponent assemblies. The 2D NOESY experiments revealed the size of the assembly, the close proximity of the encapsulated calix[4]arene molecule to the resorcinarene molecules of the capsule, and the inclusion of the tetramethylammonium cation in the calix[4]arene cavity.

Shivanyuk A.
J. Am. Chem. Soc. 2007, 129 (46), 14196-14199
DOI: 10.1021/ja067402c