Ring-closure reactions of functionalized vinyl sulfonamides
Chem. Heterocycl. Compd. 2021, 57 (6), 630-632
Diversity-oriented synthesis embodied in a strategy of pairing vinyl sulfonamide moiety with other functional groups resulted in an array of skeletally diverse 5–8-membered sultams (cyclic sulfonamides) in the fewest possible steps. In particular, this strategy allows utilization of a number of cyclization protocols including intramolecular Michael, Diels–Alder, Heck, Pauson–Khand, Baylis–Hillman reactions, ring-closing metathesis (RCM) and others.