Application of chlorotrimethylsilane in Pictet–Spengler reaction
Monatshefte f ,r Chemie - Chemical Monthly 2012, 143 (11), 1507-1517
Chlorotrimethylsilane has been found to be an efficient condensing agent in the Pictet–Spengler reaction, affording an extremely straightforward synthetic route to tetrahydro-β-carboline derivatives and their analogs. The applicability of the method has been studied, and a representative library of structurally diverse products has been created.
Ryabukhin S.; Panov D.; Plaskon A.; Tolmachev A.; Smaliy R.
Monatshefte für Chemie - Chemical Monthly 2012, 143 (11), 1507-1517