A Facile Synthesis of Imidazo[1,5-b]pyridazines from 3-Formylchromones
Heterocycles , 2008, 75 (7), 1765-1772
The recyclization of 3-formylchromones promoted by chlorotrimethylsilane with 1-amino-1H-imidazoles results in a set of imidazo[1,5-b]pyridazines is obtained in high preparative yields. It's found that the reaction is sensitive to the structure of NNC-binucleophiles.
Ryabukhin S. V.; Plaskon A. S.; Volochnyuk D. M.; Shivanyuk A. N.; Tolmachev A. A.
Heterocycles 2008, 75 (7), 1765-1772