Collaboration leverages PAL’s public research facilities and Enamine’s compound libraries and fragment progression support to accelerate fragment-based lead discovery (FBLD).
Pohang, Republic of Korea, and Kyiv, Ukraine — MAY 13 2026 – Enamine Ltd., a global leader in chemical synthesis and compound libraries, has partnered with the Pohang Accelerator Laboratory (PAL), a government funded, non profit research facility in the Republic of Korea, to establish a collaborative framework for crystallographic fragment screening.
Collaboration creates a unique partnership model: PAL provides open access to advanced crystallography infrastructure as part of its public mission, while Enamine contributes to commercial compound libraries and rapid hit to lead chemistry services. Together, they lower barriers for both academic researchers and industry partners, combining subsidised access to innovation.
Key collaboration benefits include:
- Access to experimentally refined fragment libraries and automated screening workflows
- Flexible cooperation models tailored to research needs
- Rapid fragment progression and hit to lead support from Enamine’s global resources
This partnership blends public research infrastructure with private sector agility, making drug discovery faster, more accessible, and more collaborative,
said Iaroslava Kos, PhD, Director, Business Development at Enamine.
Tetiana Matviiuk, PhD, Principal Scientist, Head of Library Design at Enamine, added: Fragment based discovery is most powerful when structural insights are immediately supported by rational hit follow up. Enamine’s fragment libraries are designed to be synthetically tractable from the outset, enabling efficient structure guided optimization. In combination with PAL’s crystallographic screening expertise, this collaboration allows progression of fragment hits toward meaningful chemical probes and lead compounds with rigour and speed.
At PAL, we strive to support global researchers by providing reliable access to advanced crystallographic infrastructure,
said Jae-hee Jeong, Staff Engineer and X-FBDD Facility Lead at Pohang Accelerator Laboratory. Through this collaboration with Enamine, we expect to enhance structure-based research by integrating advanced experimental data with top-tier chemical expertise.