A Subset of Enamine REAL Compounds, Valuable Addition to The REAL/xREAL Space
Enamine unREAL® Space is a new, original extension to Enamine REAL compounds.
This collection is broad and diverse, opening a much larger access to synthetically accessible chemical space for drug discovery. All compounds from the unREAL Space are available in the shortest possible time thanks to well-established and validated synthesis protocols. The unREAL Compounds are assembled using 24 unique, well-validated synthetic protocols not included in the REAL/xREAL Space.
Key Facts
- Over 73 billion new, unique compounds that complement the REAL/xREAL Space
- Over 38 billion compounds compliant with Ro5, and over 33 billion compounds compliant with Veber's rule
- Shipping from 4 weeks
- Over 80% of compounds delivered
- All compounds undergo extensive quality control by 1H NMR and LC-MS, and purity is guaranteed to be over 90%.
Applications
- Hit finding
- SAR and hit-to-lead
- Compound library extension
Novelty
The unREAL Compounds are an innovative dataset of screening compounds that unlocks access to billions of previously unknown, unique structures. Enamine specialists continuously develop new and original building blocks, expanding access to an infinite chemical space for drug discovery. In most cases, Enamine provides the ability to supply these compounds without publishing them in their in-stock catalogs and online databases (Reaxys, SciFinder, Pubchem, etc.).
Diversity
The unREAL Space is built on 620 million Bemis-Murcko scaffolds that are unique and not present in the REAL/xREAL Space. This incredible diversity of scaffolds is made possible by utilizing over 130,000 unique building blocks assembled via 24 synthetic protocols.
Accessibility
The unREAL Space and its subsets are available upon request. Please send us an inquiry to