Vinyltrimethylsilane

CAS 754-05-2, Cat. No EN300-111842
Ethylene equivalent reagent

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Vinyltrimethylsilane is a versatile reagent used in organic synthesis as an ethylene equivalent in electrophilic substitution reactions¹. Its applications include the synthesis of aryl vinyl sulfides, aldehydes homologation, and the formation of 3-trimethylsilyl-3-buten-2-one, which is useful for Robinson annulations. The reagent participates in [3+2] cycloadditions, forming isoxazolidine adducts, and is key in the synthesis of α,β-unsaturated aldehydes¹. Vinyltrimethylsilane is highly flammable and hygroscopic. It should be handled with care under well-ventilated conditions. The reagent is typically stored in a cool, dry place away from moisture due to its reactivity with protic solvents.

Synonyms: trimethyl(vinyl)silane; ethenyltrimethylsilane; silane, ethenyltrimethyl-; trimethylvinylsilane; (trimethylsilyl)ethylene; silane, trimethylvinyl-; ethenyl(trimethyl)silane; vinyl trimethylsilane; vinyltrimethylsilane