CAS 2526-64-9, Cat. No EN300-1698807
Reagent for chlorination
Triphenylphosphine dichloride is a versatile reagent in organic synthesis, utilized for converting alcohols to alkyl chlorides, carboxylic acids to acyl chlorides, and epoxides to vicinal dichlorides[1]. It is highly sensitive to moisture, necessitating storage under dry conditions and careful handling. Specific applications include the chlorination of allylic alcohols, the preparation of iminophosphoranes, and the cleavage of esters to acid chlorides. The reagent provides high regio- and stereoselectivity, making it valuable for various synthetic transformations in chemistry.
Synonyms: dichlorotriphenylphosphorane; triphenyldichlorophosphorane; chlorotriphenylphosphonium chloride
Selected publication
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Triphenylphosphine Dichloride.
Dormoy J.; Castro B. Encyclopedia of Reagents for Organic Synthesis 2001. DOI: 10.1002/047084289X.rt371