tert-Butyl 1,1-dimethylallyl carbonate

CAS 861216-48-0, Cat. No EN300-46734425
Reagent for prenylation

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tert-Butyl 1,1-dimethylallyl carbonate is a prenylation reagent. It is capable of effective prenylation of alcohols and amines. The reagent enables a scalable and efficient approach for synthesizing N-reverse prenylated indoles, offering a straightforward alternative to multistep or catalyst-heavy methods. This methodology is effective for nonactivated indoles, tolerating a wide variety of functional groups, including halogens, esters, and nitro groups¹.

Synonyms: 1,1-dimethylethyl 1,1-dimethyl-2-propen-1-yl carbonate; carbonic acid, 1,1-dimethylethyl 1,1-dimethyl-2-propenyl ester; tert-butyl (2-methylbut-3-en-2-yl) carbonate; tert-butyl 1,1-dimethylallyl carbonate