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CAS 178439-26-4, Cat. No EN300-7401892
Reagent for fluorination

SynFluor

N,N'-Difluoro-2,2'-bipyridinium bis(tetrafluoroborate) (SynFluor) is a highly reactive electrophilic fluorinating reagent, widely used in the synthesis of various organofluorine compounds1. It is stable at room temperature but undergoes exothermic decomposition over 160°C. SynFluor effectively fluoridates β-diketones, β-ketoesters, phenols, anisoles, phenylurethanes, and steroid derivatives under mild conditions2. The reagent is supplied as a white powder and should be handled cautiously in a dry atmosphere.

Synonyms: 1,1′-difluoro-2,2′-bipyridinium bis(tetrafluoroborate); N,N'-difluoro-2,2'-bipyridinium bis(tetrafluoroborate); 1,1'-difluoro-[2,2'-bipyridine]-1,1'-diium tetrafluoroborate; MEC-31

Selected publication

  1. 1,1′-Difluoro-2,2′-Bipyridinium Bis(Tetrafluoroborate).

    Singh R.; Umemoto T. Encyclopedia of Reagents for Organic Synthesis 2008. DOI: 10.1002/047084289X.rn00849

  2. Exploration of Fluorination Reagents Starting from FITS Reagents.

    Umemoto T. J Fluor Chem 2014, 167, 3–15. DOI: 10.1016/j.jfluchem.2014.07.029

 

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