Divinyltetramethyldisiloxane

CAS 2627-95-4, Cat. No EN300-6490756
Reagent for vinylation and cross-coupling

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1,3-Divinyltetramethyldisiloxane (DVDS) is a versatile reagent with applications in organometallic synthesis, particularly in forming metal complexes and as a precursor in silylative couplings¹. It is widely used as a ligand to form metal precatalysts with Pt, Pd, Ni, Rh, etc. DVDS is an inexpensive, less toxic, and more accessible vinyl cross-coupling reagent. The Hiyama cross-coupling of 1,3-divinyltetramethyldisiloxane with various iodo- and bromoarenes in the presence of catalyst affords functionalized styrenes. The reagent is a moisture-sensitive, colorless oil that hydrolyzes in water slowly. It should be stored under anhydrous conditions and is incompatible with strong oxidizers and halogens.

Synonyms: DVDS; 1,3-divinyltetramethyldisiloxane; 1,1,3,3-tetramethyl-1,3-divinyldisiloxane; disiloxane, 1,3-diethenyl-1,1,3,3-tetramethyl-; ethenyl-[ethenyl(dimethyl)silyl]oxy-dimethylsilane; 1,1'-divinyltetramethyldisiloxane; bisvinyltetramethyldisiloxane; sym-tetramethyldivinyldisiloxane; 1,3-diethenyl-1,1,3,3-tetramethyldisiloxane; 1,3-diethenyl-1,1,3,3-tetramethyl disiloxane; tetramethyl-1,3-divinyldisiloxane; 1,3-divinyl-1,1,3,3-tetramethyl disiloxane; disiloxane, 1,1,3,3-tetramethyl-1,3-divinyl-; ethenyl[(ethenyldimethylsilyl)oxy]dimethylsilane