The organic chemistry of the pentafluorosulfanyl group (SF5) has been known since 1950’s. As the SF5-group is larger and more lipophilic than the CF3-one, it is often considered as a “super-trifluoromethyl group." Over the past decade, the SF5–containing organic compounds already found great practical application in argochemistry and medicinal chemistry.
Properties
- One of the most electron-withdrawing groups
- high chemical and thermal stability
- high lipophilicity
Our offer
>30 SF5-buiding blocks in gram amounts in stock. Custom synthesis of further analogues and compound libraries
