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The indolizine analogues represent an important class of privileged heterocyclic scaffolds, pivotal in modern drug design. Their purine-like topology makes them particularly valuable in kinase-targeting drugs. Among these, the [1,2,4]triazolo[1,5-a]pyridine scaffold stands out, having already yielded two approved clinical drugs, tucatinib and filgotinib, and numerous others in clinical trials. Explore our collection of over 100 triazolopyridines to find the ideal candidates for your molecular engineering needs.

Triazolopyridine Scaffold

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Case study: Triazolopyridine Scaffold

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Over 100 triazolopyridines from stock on 5-10 gram scale.

 

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