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Chloroformates, also known as carbonochloridates, provide easy access to organic carbamates and carbonates, key structural motifs in numerous approved drugs and pharmaceutical intermediates. The rapid reactivity with amines and alcohols under mild conditions delivers excellent selectivity and high yields. Recent advancements have expanded the utility of chloroformates with novel organic transformations, including coupling reactions. Explore Enamine’s latest collection of approximately 200 chloroformates to diversify your compound libraries and unlock new synthetic possibilities!

Chloroformates for Medicinal Chemistry

Case study

Case study: Chloroformates for Medicinal Chemistry

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Over 100 chloroformates from stock on 5-10 gram scale.

 

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