Secondary amines are important reagents for the carbon–nitrogen bond formation, which is necessary in organic synthesis and medicinal chemistry. Enamine offers over 20 000 secondary amines from stock ranging from small decorating building blocks to intermediates and complex scaffolds for library synthesis. Our collection is the largest in the world being continuously enriched with novel secondary amins that we design and synthesize in our labs.
Every month we synthesize hundreds of new secondary amines that we immediately commercialize in our catalog available for browsing at EnamineStore. It is only with a delay sometimes of a few months that the new and in many cases unique items are published in the established aggregator platforms. If you are looking for original recently synthesized building blocks we encourage you to use our focused selection of 6 months.
Our secondary amine-containing scaffolds are represented by a considerable number of readily available building blocks bearing at least two variation points for possible selective modifications.
Secondary amines have found a wide application in synthesis of compound libraries first of all because of smoothly running amide coupling, arylation, alkylation, reductive amination reactions etc. Using our in-house developed reactivity filters we have selected a range of secondary amines that can provide clean reactions and high yields of the products. All compounds having side functionalities that interfere under majority of the reaction conditions have been removed from this set. Such set of secondary amines can be easily shared on your request.
Having synthesized thousands of secondary amines and having numerous starting materials in stock we can easily use our skills and documented knowledge to synthesize in short term analogous compounds to what we publish in our catalog. We have gathered our ideas of such new building blocks in a database that can be shared on request.