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Secondary amines

Secondary amines are important reagents for the carbon–nitrogen bond formation, which is necessary in organic synthesis and medicinal chemistry. Enamine offers over 19 000 secondary amines from stock ranging from small decorating building blocks to intermediates and complex scaffolds for library synthesis. Our collection is the largest in the world being continuously enriched with novel secondary amins that we design and synthesize in our labs.

Secondary amines

 
Aliphatic
Aromatic
Bicyclic

Item

Original

Aliphatic


EN300-1704276

Aromatic


EN300-218717

Bicyclic


EN300-89735

Item

Fluorinated

Aliphatic


EN300-94689

Aromatic


EN300-27853

Bicyclic


EN300-114809

Item

Bifunctional

Aliphatic


EN300-55884

Aromatic


EN300-23678

Bicyclic


EN300-89740

Novel secondary amines

Every month we synthesize hundreds of new secondary amines that we immediately commercialize in our catalogue available for browsing at EnamineStore. It is only with a delay sometimes of a few months that the new and in many cases unique items are published in the established aggregator platforms. If you are looking for original recently synthesized building blocks we encourage you to use our focused selection of 6 months.

Scaffolds

Our secondary amine-containing scaffolds are represented by a considerable number of readily available building blocks bearing at least two variation points for possible selective modifications.

Building blocks for parallel synthesis

Secondary amines have found a wide application in synthesis of compound libraries first of all because of smoothly running amide coupling, arylation, alkylation, reductive amination reactions etc. Using our in-house developed reactivity filters we have selected a range of secondary amines that can provide clean reactions and high yields of the products. All compounds having side functionalities that interfere under majority of the reaction conditions have been removed from this set. Such set of secondary amines can be easily shared on your request.

Special subsets

Fluorinated secondary amines

N-monoprotected diamines

Amino acids and their derivatives

Bi- and polycyclic secondary amines

REAL secondary amines

Having synthesized thousands of secondary amines and having numerous starting materials in stock we can easily use our skills and documented knowledge to synthesize in short term analogous compounds to what we publish in our catalogue. We have gathered our ideas of such new building blocks in a database that can be shared on request.

Services

Enamine offers world class service in chemical synthesis of a wide variety of organic compounds on the milligram to kilogram scale at competitive price.

Library Synthesis

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