medCHEMbio2020 - Enamine

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Building Blocks
Functional classes

DEL-compatible scaffolds
Azides / Click Chemistry
Carboxylic acids
Aldehydes
Alkyl Halides
Aryl Halides
Boronic Acid Derivatives
Primary Amines
Secondary Amines
Sulfonyl Chlorides/Fluorides
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MedChem Highlights

Aliphatic Trifluoroborates (-BF₃) for C-C couplings
Functionalized Vinyl Boronates for C-C couplings
Unique 3D-shaped Spirocycles to Explore Novel Chemical Space
Water-soluble non-classical benzene mimics
gem-Difluorinated Amines for Drug Design
Fluorosulfates and Sulfamoyl Fluorides for Drug Design
Alkyne-containing Linkers
Structurally optimized tetrazines for rapid biological labeling
Building blocks and linkers for PROTAC synthesis
Heterocyclic Sulfonyl Fluorides
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Synthesis of New Building Blocks

Make-on-Demand Building Blocks
Custom Synthesis
Chiral separation
Library Synthesis
REAL Compounds

REAL Database
REAL Space
REAL Compound Libraries
Programs

Scaffold Decoration
Compound Collection Enhancement
FTE Chemistry Support
Hit Finding
Diversity Libraries

10 560 compounds
50 240 compounds
Hit Locator Library
Phenotypic Screening Library
Covalent Screening Library
Targeted Libraries

Antiviral Library
GPCR Library
PPI Library
CNS Library
Coronavirus Library
RNA Library
Glycomimetic Library
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Compound collections

Screening Collection
REAL Database
Fragments
Covalent Compounds
Macrocycles
BioReference Compounds
Services

High-Throughput Screening
In silico modeling
Hit exploration
REAL Space
Fragments
Plated Libraries

DSI-poised Library
Essential Fragment Library
High Fidelity Fragment Library
Covalent Fragment Library
Natural Product-like Fragments
3D Shape Diverse Library
PPI Fragment Library
Covalent Fragments

Warhead Subsets
CYS focused Library
SER focused Library
LYS focused Library
Acrylamides
Fragment Collection

MiniFrag Library
sp³ Rich Fragments
Single Pharmacophore
Carboxylic Acid Fragments
Fluorinated Fragments
Services

Analogues search
Turbidity assay
Fragments pooling
Discovery
Chemistry services

Library synthesis
Custom synthesis
FTE Chemistry Support
Biology services

High-Throughput Screening
In vitro ADME
In vivo PK/Tox
Functional Compounds

CeMM Library of Unique Drugs (CLOUD)
BioReference Compounds
Impurity Reference Standards

Building Blocks
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MedChem Highlights
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