Protein Degradation Toolbox

Ready-to-use tools for your discovery

The recently emerged therapeutic area that modulates the ubiquitin-proteasome system needs new and reliable chemistry. Booming biological assays in this field of drug discovery require the production of hundreds and thousands of new functional intermediates, bifunctional molecules, and new molecular glues. The time needed to produce new derivatives is crucial at any stage of the drug discovery program. We offer advanced synthetic chemistry support, including custom library design and synthesis.

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Cereblon ligands and ligands with linkers

Cereblon focused products

VHL ligands and ligands with linkers

VHL ligands and intermediates

SPLicing inhibitor sulfonAMides

DCAFs focused ligands

Linkers for Linkerology

Linkers

Active Degraders
Ligand-linkers conjugate Kits

E3 Ligand-Linkers Conjugate Kits

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