In vivo PK/Tox


Pharmacokinetics (PK) reveals the fate of substances in the body over time. The compounds can be administered in multiple ways, among which peroral (PO) and intravenous (IV) are the most popular ones. Cassette dosing in the PK study allows for understanding of the drugs interaction in vivo system.

All PK studies can be customized upon request.


In vivo models

In vivo models play a pivotal role in the drug discovery process. Evaluation of the lead compounds in living organisms for safety and efficacy remains one of the main requirements before clinical studies in humans. In our studies, we thrive to minimize the use of vertebral animals and substitute assays for evaluation of the lead compounds with in vitro models whenever possible. However, some complex diseases, e.g. diabetes, require enrolment of experimental animals.

Our bioanalytical laboratory possesses the national regulatory certification for providing bioanalytical support of clinical bioavailability and bioequivalence studies.

We work closely with our customers to develop an ADME/PK program specifically tailored to their project needs, ensuring flexible approach depending on the requirements and specifications. We can develop or modify specific methods according to what is requested, including high-throughput ADME analysis and Express ADME panel to accomodate large sets and strict deadlines.

Animal Studies

Rodent Models


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